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Scientists can make an enormous difference in the world.

Take the researcher Sarah Gilbert, who has dedicated her career to developing vaccines. Over the last two decades, she has contributed to vaccines against the flu, MERS, Nipah virus, and Rift Valley fever. When she heard about the outbreak in China in January 2020, she began working on a vaccine, just in case. By the end of that year, the vaccine against COVID-19 was approved, saving an estimated 6.3 million lives in the following year alone. Without this effort, we would have faced a much darker reality, marked by lockdowns, overwhelmed health systems, and widespread suffering.

This chart lists many such scientists whose work saved many people’s lives. The estimates are taken from the web publication Science Heroes, where you can find profiles of these scientists.

It’s difficult to estimate the exact difference particular innovations have made, and I take all such estimates with a grain of salt. None of these scientists did their work in isolation; their innovations were achieved thanks to collaborative efforts and the earlier work of other researchers.

Our team spends much of its time counting deaths, but it’s equally important to know the number of lives saved — even though it is harder to estimate and involves much larger uncertainty. It’s inspiring to be reminded that creative, enterprising, and tenacious people can enormously contribute to our lives.

Fritz Haber and Carl Bosch, who invented synthetic fertilizers, are at the top of this list. My colleague Hannah Ritchie wrote an article about the difference their work has made: How many people does synthetic fertilizer feed? →

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China’s patent applications have grown rapidly in recent decades, as shown in the chart. Chinese applications surpassed US applications in 2010, reaching over 1.4 million in 2021. According to this data from the World Intellectual Property Organization (WIPO), China’s applications accounted for more than half of the global total in 2021.

In contrast, patent applications in the US have seen little growth in recent years, while in Japan, filings have steadily declined since 2000.

Innovations are patented due to economic incentives. A patent protects the invention to the owner for a limited period, often 20 years. This is why policymakers and researchers frequently compare annual patent filings across countries — new patents are considered a proxy for the pace of innovation.

However, patents are just one aspect of innovation. A country’s innovation system is shaped by a complex network of research, development, and commercialization, and patent applications are just one part of this broader process.

Read more about technological progress →